Data Analytics & Computational Sciences

Data Science

Scientific/Technology

Spring House, PA (preferred); Cambridge, MA; San Diego, CA (La Jolla area); Titusville, NJ; Raritan, NJ.

Johnson & Johnson Innovative Medicine is recruiting for a Principal Data Scientist - Oncology to join the Data Science and Digital Health team (DSDH). This position will be located in one of the listed locations (Spring House, Cambridge, San Diego; optional Titusville, Raritan). The Principal Data Scientist - Oncology will play a pivotal role in standardizing and connecting biomedical and clinical data. The role is a hands‑on technical contributor with depth in semantic technologies, ontology, and graph data modeling, and strong familiarity with the life sciences domain.

• Be a key contributor to the design and implementation of a scalable knowledge graph infrastructure focused on data standardization and interoperability, focusing on Oncology R&D data.
• Apply graph‑based data modeling for efficient Oncology R&D organization, integration and retrieval to ensure system flexibility and long‑term maintainability.
• Work with a larger community of Data Scientists, Clinical Scientists, and Discovery Scientists to standardize, curate and create AI‑Ready datasets.
• Curate and extend ontologies for clear mapping into established biomedical ontologies and controlled terminologies using resource description framework (RDF) standards.
• Work with SPARQL/GraphQL/REST services; develop ingestion and curation pipelines to ingest, normalize and map concepts across data sources.
• Extend and curate Oncology R&D‑relevant ontologies (e.g., diseases, drugs, targets, pathways, etc.) and maintain synonyms, cross‑references, and provenance.
• Partner with cross‑functional teams to enable NLP/RAG over graphs, features for predictive modeling and terminology services for search and study design tools.
• Work with Data Science & Digital Health colleagues, IT and DevOps teams to deploy and manage the graph database infrastructure, focusing on high availability, scalability, and recovery operations specifically geared toward Oncology R&D needs and applications.
• Draft and manage documentation, such as data dictionaries, data lineage, and data flow diagrams, to facilitate understanding of the knowledge graph.

• Desired Ph.D. or Master’s degree in bioengineering, computer science, IT, bioinformatics, physics, mathematics, or related fields, emphasis on semantic technologies for biomedical application.
• 5+ years professional experience in health informatics.
• Demonstrated experience in large‑scale knowledge graphs construction, ontology development, pharmaceutical or healthcare domains integration.
• Programming background in parser combinators, natural language processing, and linked data (RDF Triple Stores and property graphs).
• Proficiency in semantic web technologies (e.g., SPARQL, RDF, OWL), familiarity with graph databases (Neo4j, Amazon Neptune).
• Proven work with complex biomedical datasets (e.g., clinical, genomics, proteomics).
• Proficiency in various data storage solutions (SQL, key‑value, column, document, graph stores) and data modeling techniques (semantic data, ontologies, taxonomies).
• Experience in CI/CD implementations, git usage, CI/CD stacks (Jenkins, GitLab, Azure DevOps), DevOps tools, metrics/monitoring, and containerization technologies (Docker, Singularity).
• Demonstrated stakeholder management capabilities—including requirements gathering, business analysis and planning. Must have the capacity to translate discussions into user requirements and project plans.
• Ability to manage a numerous projects simultaneously, prioritize work, exhibit organizational skills and flexibility to deliver maximum business value.
• Willingness to conduct periodic travel (<15% of time) to conferences and internal meetings.

Compensation and benefits: The anticipated base pay range for this position is $117,000 to $201,250. The company offers performance‑based compensation, annual performance bonuses, and comprehensive benefits including medical, dental, vision, life insurance, short‑ and long‑term disability, business accident insurance, group legal insurance, a 401(k) plan, vacation (up to 120 hours per calendar year), sick time (up to 40 hours per calendar year), holiday pay and floating holidays (up to 13 days per calendar year), and additional time‑off benefits. Additional information can be found at https://www.careers.jnj.com/employee-benefits.

If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers , internal employees contact AskGS to be directed to your accommodation resource.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.