Sr. Director, Sales Operations & Commercial Excellence

About Cerenome

Cerenome (Nasdaq: CNSY) is a clinical-stage central nervous system (CNS) oncology company focused on transforming how rare and severe brain and spinal cancers are diagnosed, monitored and treated. Our work brings together advanced diagnostics, targeted radiotherapeutics and data analytics to address some of the most difficult challenges in neuro-oncology. Our portfolio includes CNSide®, our proprietary cerebrospinal fluid-based diagnostic platform, and REYOBIQ™, our investigational radiotherapeutic currently in clinical development.

We are a growing company, which means many of the systems, capabilities and ways of working that will support our next stage are being built now. We see that as an opportunity—and we're looking for people who do, too.

The Role

Cerenome is looking for a Senior Director, Sales Operations & Commercial Excellence to help build the commercial infrastructure required for our next stage of growth. This is not a role where you'll inherit a mature Sales Operations function and optimize what's already there. You'll work closely with our Vice President of Commercial Sales and other leaders to build much of the foundation from the ground up starting with two immediate priorities: territory design and sales incentive compensation.

As our commercial organization grows, you'll help determine how we structure territories and accounts, measure performance, use commercial data, manage our CRM, forecast the business and create operating processes that can scale with us.

We're looking for someone who has built before. You'll need to be comfortable setting strategy, making recommendations to senior leaders and then rolling up your sleeves to create the models, processes and tools that turn those decisions into something the organization can actually use.

Key Priorities

• Build our territory and account model. Develop the initial territory architecture for our growing field organization, including account segmentation, targeting, coverage, capacity and resource-allocation considerations. Continue to evolve the model as the business and commercial team grow.


• Design our sales incentive compensation approach. Partner with Commercial Leadership, Finance and HR to develop incentive plans that reinforce the right commercial behaviors and business outcomes. Build the underlying quota structures, performance measures, payout mechanics and modeling needed to administer and evaluate the plans effectively.


• Create a reliable commercial data and CRM foundation. Help establish HubSpot as a disciplined source of commercial information, including appropriate data structure, workflows, pipeline management, reporting and governance. Build the infrastructure with an eye toward what Cerenome may require as the commercial organization becomes larger and more complex.


• Give leaders meaningful visibility into the business. Develop practical dashboards, forecasts, KPIs and reporting that help Commercial Leadership and the Executive Management Committee understand performance, productivity, opportunities and emerging risks—and make better decisions from the data.


• Build commercial processes that can scale. Establish the operating rhythms, workflows and governance needed to support a growing sales organization. Look for opportunities to simplify and automate work rather than creating processes that become heavier as the organization grows.


• Help shape what comes next. Partner with Commercial, Marketing, Finance, HR and other teams on commercial planning, sales capacity and organizational growth. As Cerenome expands its commercial footprint, help us determine when existing infrastructure needs to evolve and what additional capabilities will be required.

Experience & Capabilities

We're looking for someone with significant experience in Sales Operations, Commercial Excellence, Revenue Operations, Commercial Analytics or a closely related discipline, ideally gained within diagnostics, biopharma, laboratory services, life sciences, healthcare or another complex commercial environment.

Just as importantly, we're looking for evidence that you've built, not simply managed, commercial infrastructure.

That includes:

• Experience personally designing or substantially building territory and account models and sales incentive compensation programs.


• Strong knowledge of sales planning, quota setting, forecasting, pipeline management, performance measurement and commercial analytics.


• Hands-on CRM experience, including data structure, workflows, reporting, dashboards and governance. Our current commercial platform is HubSpot.


• Strong analytical capability and the ability to turn imperfect or disparate data into useful business insight.


• Experience developing practical dashboards, forecasting models and executive-level commercial reporting.


• The ability to work effectively across Commercial, Finance, Marketing, HR and other functions where priorities and perspectives may differ.


• Comfort operating at both strategic and tactical levels. At this stage of our growth, you'll often be the person designing the solution and helping build it.


• The judgment and communication skills to advise senior leaders, challenge assumptions when appropriate and translate decisions into practical execution.

A bachelor's degree or equivalent combination of education and relevant experience is expected.

Additional Experience We Value

Experience in oncology, molecular diagnostics, precision medicine or laboratory services would be particularly relevant to our work.

We'd also value experience supporting the commercialization of a new product or emerging technology; building Sales Operations capabilities during significant organizational growth; advanced HubSpot or Salesforce experience; CRM implementation or migration; and experience integrating commercial, marketing, financial or other business data.

Technical experience with data, analytics, APIs or related tools can be valuable, but we're more interested in what you've been able to build and enable with technology than in collecting a particular list of technical credentials.

Position Details

Reports to: Vice President, Commercial Sales

Employment Type: Full-time

Location: Remote or Hybrid

Travel: Approximately 15–25%, based on business needs

The role is expected to evolve as Cerenome's commercial organization grows and may eventually include responsibility for building and leading a Sales Operations/Commercial Excellence team.