Laboratory Manager

We are seeking an experienced Lab Manager / General Laboratory Supervisor (GLS) to lead day-to-day operations for a growing, high-complexity clinical toxicology laboratory.

This is a hands-on leadership role for someone who can oversee laboratory workflow, manage and troubleshoot LC-MS/MS instrumentation, lead method development and validation, supervise staff, and maintain strong regulatory compliance. The lab is expanding its capabilities with an additional LC-MS/MS platform and the launch of oral fluid toxicology testing.

Key Responsibilities

• Oversee daily clinical toxicology laboratory operations, including workflow, turnaround time, quality, and instrument performance.


• Lead method development and validation for new analytes, matrices, and testing platforms.


• Maintain, troubleshoot, and optimize LC-MS/MS instrumentation, including Shimadzu LCMS-8050 and Sciex 5500 platforms.


• Ensure compliance with CLIA, COLA, CAP, QC, proficiency testing, SOP, and documentation requirements.


• Supervise, train, and develop laboratory personnel.


• Work closely with the Medical Director on new test implementation, workflow approvals, and inspection readiness.


• Identify opportunities to improve efficiency, quality, and laboratory performance.


• Manage reagents, consumables, vendors, and instrument service relationships.


• Report operational KPIs, staffing needs, and expansion readiness to leadership.

Required Qualifications

• Bachelor’s degree or higher in clinical laboratory science, chemistry, biology, or a related field.


• 3–5+ years of hands-on LC-MS/MS experience within a clinical toxicology laboratory.


• Experience developing and validating new methods, analytes, matrices, or instruments.


• Strong knowledge of high-complexity laboratory regulatory requirements.


• Previous leadership or supervisory experience.


• Ability to obtain a Nevada General Laboratory Supervisor license; sponsorship and support are available.

Preferred Experience

• Oral fluid toxicology method development and validation.


• MLS (ASCP) or similar certification.


• Experience within behavioral health, substance use disorder, pain management, or clinical toxicology laboratories.


• Experience building or managing a small laboratory team.

Compensation & Benefits

• $90K–$110K base salary, depending on experience.


• Full relocation package.


• Health insurance and PTO.


• Professional development support.


• Significant autonomy and opportunity to take on additional responsibility as the laboratory expands.