Biomedical Scientist II

Scarless Laboratories Inc. Torrance, CA Open

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Scarless Laboratories Inc. is looking for Biomedical Scientist II in Torrance, CA.
This local job opportunity with ID 3817864850 is live since 2026-09-04 09:04:08.
Peptide Drug Development & Molecular Biology Design and execute experiments for the development of peptide-based therapeutics targeting cell signaling pathways involved in wound healing and tissue regeneration. Arrange peptide synthesis, purification, and characterization; evaluate peptide stability, bioactivity, and binding affinity using advanced molecular techniques. Conduct complex cell culture experiments to assess the efficacy of therapeutic peptides on primary cell lines (e.g., keratinocytes, fibroblasts, and tenocytes) regarding gene expression and differentiation. Perform PCR/qPCR, Western Blot, IHC, and Molecular Cloning while operating specialized analytical equipment, including FACS and HPLC. In Vivo Disease Modeling & Therapeutic Evaluation Develop and manage specialized animal models to test peptide efficacy, including STZ-induced diabetic swine for diabetic foot ulcer (DFU) studies and porcine/rodent models for hypertrophic scar (HTS) formation. Perform surgical creation of tendon lesions and implement therapeutic interventions to study tendon injury and repair mechanisms. Manage real-time glucose monitoring, medication administration, and sample collection for diabetic swine and rodent subjects, ensuring meticulous record-keeping and coordination with veterinary staff. Implement chronic and acute skin wound models, providing specialized post-procedure care and monitoring for tissue remodeling and scar prevention. Biomechanical & Imaging Analytics Evaluate the mechanical properties of repaired tendons and skin tissues using universal testing machines (e.g., Instron or MTS) to determine tensile strength and viscoelasticity. Quantify functional recovery in tendon repair models using automated gait analysis systems (e.g., CatWalk XT) to synthesize locomotion data. Utilize high-resolution 3D clinical photography and wound reconstruction platforms (e.g., QuantifiCare LifeViz) to track and analyze 3D wound volume and healing trajectories. Develop and optimize topical and injectable peptide delivery systems, including hydrogel and cream formulations for chronic and acute wound applications. Regulatory Compliance & Clinical Translation Coordinate immunogenicity testing and antibody production to support pre-clinical safety assessments of lead peptide candidates. Bridge the transition from pre-clinical results to clinical study needs by drafting research protocols, safety report forms, and annual regulatory updates. Ensure all research activities strictly comply with FDA regulations and institutional guidelines; maintain research practices in accordance with Good Clinical Practice (GCP) and HIPAA regulations during data capture in EDC systems. Manage project logistics, including research quality management, clinical trial recruitment logistics, and strategic planning for research budgets and timelines using software such as Notion and Gantt charts. Minimum Requirements: Masters in Stem Cell and Regenerative Medicine, or a closely related field. 12 months experience in medical device QC or clinical lab environment, including mechanical testing; regulatory compliance (GDP, HIPAA, or FDA); molecular biology (PCR, Western Blot, IHC, cloning); or in vivo research, including animal handling and tissue processing. read more

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